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News, Articles and Publications on AK

Below a summary of interesting articles and publications in regard to Acanthamoeba Keratitis (AK) and Contact Lenses related.

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Effectiveness and Safety of Topical Chlorhexidine and Vitamin E TPGS in the Treatment of Acanthamoeba Keratitis: A Survey on 29 Cases by Caruso, C.; Eletto, D.; Rinaldi, M.; Pacente, L.; Troisi, S.; Semeraro, F.; dell’Omo, R.; Costagliola, C. – MDPI – (2020)

SIFI Completes Enrollment of the Phase 3 Study of Polihexanide 0.08% for the Treatment of Acanthamoeba Keratitis – Eye Wire – (2020)

Application of Histone Deacetylase Inhibitors MPK472 and KSK64 as a Potential Treatment Option for Acanthamoeba Keratitis by Lee H-A, Park S-M, Chu K-B, Quan F-S, Kurz T, Pflieger M, Moon E-K. 2020. – American Society for Microbiology – (2020)

Theramoebics, is developing a prescription therapeutic that can be compounded into eye drops to effectively treat AK and greatly reduce the risk of reinfection. – University of Georgia – (2020)

Man presents with red, painful eye after foreign body injury By Allison V. Coombs, DO and Naveen K. Rao, MD – Helio – (2020)

Development of Rapid Identification System for Acanthamoeba – Hari Peguda – Supervisors: Professor Mark Willcox, Dr Nicole Carnt, Dr Sophia Gu – UNWS – (2020) 

Acanthamoeba Keratitis: Perspectives for Patients by Stefano Bonini, Antonio Di Zazzo, Giuseppe Varacalli, MD & Marco Coassin – Current Eye Research –  (2020)

A 5-Year Review of Acanthamoeba Keratitis Related to Wearing Contact Lenses in Korea by Jo, Yeon Ji M.D.; Jang, Soo Kyung M.D.; Lee, Jieun M.D., Ph.D.; Lee, Jong Soo M.D., Ph.D.- Eye & Contact Lens: Science & Clinical Practice (2020)

Acanthamoeba keratitis: a review of biology, pathophysiology and epidemiology by Ana Gomes de Lacerda and Madalena Lira – Ophthalmic & Physiological Optics –  (2020)

Atypical Presentation of Acanthamoeba Keratitis in a Contact Lens Wearer by Nada Al-Yousuf, et al., from Arabian Gulf University (Kingdom of Bahrain), etc. (2020)

Acanthamoeba Keratitis: Member of parliament, Matthew Offord, in the United Kingdom asking the government Health Education Department of Health and Social Care about the policy to ensure that the packaging of #contactlens products display (a) clear warnings of the risk of #acanthamoebakeratitis and (b) advice on how to prevent that infection – theyworkforyou – (2020)

PCR and culture for diagnosis of Acanthamoeba keratitis by Yera H, Ok V, Lee Koy Kuet F, et al – British Journal of Ophthalmology – (2020)

Current Trends in Treating Acanthamoeba Keratitis: A Brief Narrative Review by Mauro Salducci – Sapienza University of Rome – (2020)

Oral Miltefosine as Salvage Therapy for Refractory Acanthamoeba Keratitis – Praneetha Thulasi – Hajirah N. Saeed – Christopher J. Rapuano – Joshua H. Hou – others – Ajo – (2020)

New solutions in the prevention and treatment of Acanthamoeba keratitis By Ronnie Mooney, Roderick Williams and Fiona L Henriquez – eyenews – (2020)

In Vitro Topical Delivery of Chlorhexidine to the Cornea: Enhancement Using Drug-Loaded Contact Lenses and β-Cyclodextrin Complexation, and the Importance of Simulating Tear Irrigation – ACS Publications – (2020)

Controlled in vitro delivery of voriconazole and diclofenac to the cornea using contact lenses for the treatment of Acanthamoeba keratitis  – Elsevier – Science Direct – (2020)

Alkyl-carbon chain length of two distinct compounds and derivatives are key determinants of their anti-Acanthamoeba activities – UWS – (2020)

Study shows effectiveness of ‘no water’ stickers in improved contact lens hygiene – Fight for sight – (2020)

 Why contact lenses and water don’t mix – UNSW – (2020)

 Acanthamoeba Keratitis – NCBI – (2020)

 How to keep your contact lenses clean (and what can go wrong if you don’t) by Nicole Cant – The Conversation – (2020)

 ‘No water’ stickers improves CL compliance – Insight News – (2020)

The rising incidence of Acanthamoeba keratitis: A 7-year nationwide survey and clinical assessment of risk factors and functional outcomes – Plus One – (2019)

Acanthamoeba Keratitis Fact Sheet for Healthcare Professionals – CDC – (2019)

How to diagnose and treat Acanthamoeba keratitis  – EYENewsUK – (2019)

Oral miltefosine for refractory Acanthamoeba keratitis  – Elsevier Science Direct- (2019)

Riboflavin-UVA collagen cross-linking for the treatment of acanthamoeba keratitis – AES – (2019)

The rising tide of Acanthamoeba keratitis in Auckland, New Zealand: a 7‐year review of presentation, diagnosis and outcomes by James McKelvie FRANZCO PhD Moaz Alshiakhi MBChB Mohammed Ziaei FRCOphth Dipika V Patel MRCOphth PhD Charles NJ McGhee FRANZCO DSc (2009–2016) 

Treatment of Acanthamoeba Keratitis in Mexico by Ana Lilia Pérez – Balbuena MD, Virginia Vanzzini Zago QFB.., Lorena López Quezada MD, Antonio Sierra- Acevedo MD., Ramón Naranjo Tackman MD. – SlideShare (2016)

Acanthamoeba Keratitis: A Case Study for Outbreak Investigations – Cybersight – (2018)

 Rare contact lens infection outbreak in the UK is a concern for Australia too – Financial Review – (2018)

Acanthamoeba Keratitis: What Contact Lens Wearers Need To Know By Edward S. Bennett, OD – All About Vision – (2018)

Final Report Summary – ODAK (Orphan Drug for Acanthamoeba Keratitis) – Cordis (2017)

Acanthamoeba Keratitis Fact Sheet for Healthcare Professionals – CDC (Centers for Disease Control and Prevention) – (2017)

How to Care for Your Contact Lenses and Eyes by Alan Kozarsky, MD WebMD Medical Reference –  (2017)

Caring For Soft Contact Lenses by Gina White – All About Vision – (2017)

Caring for Contact Lenses by MyEyes.com (2017)

New treatments for Acanthamoeba keratitis: review of clinical cases by Espinosa Barberi G, Miranda Fernández S, Tandón Cárdenes L. – (2017)

Therapeutic agents and biocides for ocular infections by free-living amoebae of Acanthamoeba genus by Linda Christian Carrijo-Carvalho, Viviane Peracini Sant’ana, Annette Silva Foronda, Denise de Freitas, Fabio Ramos de Souza Carvalho – PubMed – (2016)

IMPAVIDO  (miltefosine) – Orphan Designation Acanthamoeba Keratitis – (2016)

Tips for Making the Tricky Acanthamoeba Keratitis Diagnosis by  Dr. Keenan AA0 – (2016)

 What’s Living On Your Contact Lenses? – (2016)

You’re Cleaning Your Contacts Wrong, Probably – (2016)

Strategies for the prevention of contact lens‐related Acanthamoeba keratitis: a review – by Nicole Carnt Fiona Stapleton – OPO – (2016)

Riboflavin and Ultraviolet Light A Therapy as an Adjuvant Treatment for Medically Refractive Acanthamoeba Keratitis by Yasin A. Khan, Renata T. Kashiwabuchi, Suy Anne Martins, Juan M. Castro-Combs, Sachin Kalyani, Philip Stanley, David Flikier, Ashley Behrens – kalyanieye – (2011)

Acanthamoeba Keratitis Treatment – By Michael A. Saidel, MD – AAO – (2006)

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